Estradiol Compounded
Estradiol (E2) is the most potent of the three human estrogens and the primary estrogen produced by the ovaries during reproductive years. It plays a central role in regulating the menstrual cycle, maintaining bone density, and supporting vaginal and urinary tract tissue. As estradiol declines during perimenopause and menopause, symptoms such as hot flashes, night sweats, and vaginal dryness commonly follow.
CareFirst compounds estradiol in strengths and dosage forms prescribed by your provider, including topical creams and oral capsules, and can combine it with progesterone or testosterone in a single preparation when your prescriber orders combination therapy. Compounding allows your dose to be titrated precisely as your levels and symptoms change, rather than jumping between fixed commercial strengths.
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Estriol Compounded
Estriol (E3) is the weakest of the body's three estrogens and is often prescribed when a gentler estrogen effect is desired, particularly for localized vaginal symptoms such as dryness, irritation, and discomfort with intercourse. Because estriol is not available as a manufactured product in the United States, it is available only through compounding pharmacies with a prescription.
Our pharmacists compound estriol into topical and vaginal creams as well as oral capsules, and it can be combined with estradiol, progesterone, or testosterone in a single customized preparation. Strength and base are prepared to your prescriber's exact specification.
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Estriol / Estradiol Compounded
Compounding pharmacies can combine estriol and estradiol in a single preparation, letting your prescriber balance the potency of estradiol against the milder profile of estriol. The most commonly prescribed ratios are 80/20, 70/30, and 50/50 (estriol/estradiol), though as a compounding pharmacy we can prepare any ratio and strength your prescriber orders.
We compound estradiol and estrogen into topical creams, troches, and capsules, and it is frequently combined with progesterone, and sometimes testosterone, so patients can manage combination hormone therapy with one preparation instead of several. The combination is available only through compounding pharmacies and requires a valid prescription.
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Progesterone Compounded
Progesterone is prescribed alongside estrogen therapy in women with an intact uterus to protect the uterine lining, and on its own for symptoms such as sleep disturbance, mood changes, and irregular cycles during perimenopause. Many prescribers prefer progesterone itself over synthetic progestins, and compounding makes a full range of strengths and delivery routes available.
CareFirst compounds progesterone in oral capsules, topical creams, troches and lozenges, sublingual suspensions, and vaginal suppositories — one of the widest ranges of dosage forms of any hormone we prepare. If swallowing capsules is difficult, or a commercial strength has never quite matched your needs, your prescriber can specify exactly what works for you.
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Testosterone Compounded
Testosterone supports muscle mass, bone density, red blood cell production, energy, and libido in both men and women. In men, levels decline gradually with age; in women, testosterone falls around menopause or after removal of the ovaries. Because no FDA-approved testosterone product exists for women, compounded testosterone is often the only practical option when a prescriber determines low-dose therapy is appropriate.
We compound testosterone into topical creams, troches and lozenges, and other formulations at the strength your prescriber specifies — from low female-range doses to standard male replacement strengths. Testosterone is a controlled substance and is dispensed only with a valid prescription from your provider.
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DHEA (Dehydroepiandrosterone) Compounded
DHEA is a precursor hormone produced by the adrenal glands that the body converts into both estrogens and androgens. DHEA levels peak in early adulthood and decline steadily with age, and prescribers may order DHEA as part of a broader hormone optimization plan.
While over-the-counter DHEA supplements vary widely in quality and actual potency, CareFirst compounds DHEA from pharmaceutical-grade ingredients to the precise strength your prescriber orders, so the dose on the label is the dose in the capsule. Available with a valid prescription.
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DHEA / Hyaluronic Acid (Vaginal) Compounded
For postmenopausal vaginal dryness, prescribers sometimes turn to locally applied DHEA, which acts within vaginal tissue with minimal systemic absorption. Our compounded DHEA with hyaluronic acid pairs the hormone precursor with a moisture-binding agent well known for its ability to hydrate and support tissue comfort.
This combination is available only through compounding and is prepared to your prescriber's specified strength. It may be an option for women seeking a non-estrogen approach to vaginal dryness — a conversation to have with your provider, who can determine whether it fits your medical history.
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DHEA / Pregnenolone Compounded
Pregnenolone sits at the very top of the steroid hormone cascade — it is the raw material from which the body synthesizes DHEA, progesterone, cortisol, estrogens, and testosterone. Like DHEA, pregnenolone production declines significantly with age.
Our pharmacists compound DHEA and pregnenolone together in a single pharmaceutical-grade capsule at the ratio and strength your prescriber orders, simplifying regimens for patients whose providers prescribe both precursors as part of a hormone support plan. Requires a valid prescription.
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