Diethylstilbestrol (DES) Compounded

Female Canine Incontinence

Use of Diethylstilbestrol (DES) for therapeutic purposes Urinary incontinence (UI) is defined as the involuntary loss of urine during the filling phase of the bladder . At this time, there are many suspected factors contributing to the problem. Nevertheless, urinary sphincter mechanism incompetence (USMI) after spaying is the most common micturition disorder, and its medical treatment is normally successful. The underlying mechanism is not fully understood. But, we do know that hormonal changes can induce structural and functional alterations in the bladder, as well as in the urethra composition. The proposed predispositions to incontinence that follows neutering including gender, breed, body weight, obesity, tail docking, spaying technique (ovariectomy and ovariohysterectomy) and morphology or position of neck of the bladder and urethral length, have all been investigated